Genetics with large known genealogies

The population of Quebec has many interesting features for geneticists. It has diverse ancestry, it experienced rapid population growth through birth and immigration, and it is well characterized genetically. A unique feature is the existence of deep and complete genealogical records (by the BALSAC project). This provides many opportunities to learn about how populations evolve, the biology of genomes, and disease. Analyzing these large genealogical and genetic datasets requires new algorithms and statistical tools.

Some papers from the lab:

French-Canadian population history in Quebec Luke’s twitter explainer

Tracking disease mutations in time