Predicting genetic risk
How do we robustly predict genetic risk? 
Posts by Collection
portfolio
Visualizing and describing high-dimensional data
How do we even look at genetic data? 
Genetics with large known genealogies
What if we knew the genealogical tree for millions of individuals? 
Understanding human evolution
How much can we learn about human evolution from genomic data? 
Genetics in admixed populations
What happens when populations meet? 
publications
Models of local ancestry
S. Gravel, (2012). "Population genetics models of local ancestry ." Genetics 191 (607).
Mathematical and inference models for the distribution and variance of ancestry along the genome.
Inference using efficient computation of the allele frequency spectrum
J. Jouganous, W. Long, A.P. Ragsdale, S. Gravel, (2017). "Inferring the Joint Demographic History of Multiple Populations: Beyond the Diffusion Approximation ." Genetics 206 (3).
Recursion equations help infer demographic models from allele frequency data
Inference using two locus statistics
A.P. Ragsdale, S. Gravel, (2019). "Models of archaic admixture and recent history from two-locus statistics." PLoS Genet. 1008204.
A likelihood approach to infer complex demographic models using two-locus statistics
Dara visualization and topological modelling
A. Diaz-Papkovich, L. Anderson-Trocmé, C. Ben-Eghan, S. Gravel (2019). "UMAP reveals cryptic population structure and phenotype heterogeneity in large genomic cohorts." PLoS Genet. 15(11): e1008432. https://doi.org/10.1371/journal.pgen.1008432.
A method of dimensionality reduction and visualization of population genetic data.
Variational Inference with Polygenic Risk Scores
S. Zabad, S. Gravel, Y. Li "Fast and Accurate Bayesian Polygenic Risk Modeling with Variational Inference." AJHG. 110, 1 (2023)
A variational approach to polygenic risk prediction, implemented as the VIPRS software.
Genetics using large genealogies in Quebec
L Anderson-Trocmé et al, "Genes, Genealogies, and geographies of Quebec", Science 380, 849 (2023)
Exploring the emergence of population structure in Quebec. Version française ici!. Media coverage: La Presse, Les années Lumière, Radio-Canada, tout un matin, Québec Science, Le figaro, Science et avenir
Humans origins in Africa
AP Ragsdale et al, "A weakly structured stem for human origins in Africa", Nature 617, 755 (2023)
Exploring the origins of modern humans. Media coverage: NYT Nat Geo, Nature Ecology and Evolution, Le Figaro Smithsonian Magazine, reuters
software
talks
Talk 1 on Relevant Topic in Your Field
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Conference Proceeding talk 3 on Relevant Topic in Your Field
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teaching
Teaching experience 1
Undergraduate course, University 1, Department, 2014
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Teaching experience 2
Workshop, University 1, Department, 2015
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